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Obtaining of hydroalcoholic extract of Aloe vera using fresh plant material Scaling process Advance Pharmaceutical Journal

Research Articles

2017  |  Vol: 2(3)  |  Issue: 3 (May-June)
Obtaining of hydroalcoholic extract of Aloe vera using fresh plant material Scaling process

Jorge Enrique Rodríguez-Chanfrau*1, Orestes Darío LópezHernández2, Caridad García-Peña3, María Lidia González-Sanabia3, Antonio Nogueira–Mendoza3

1Department of Physical Chemistry, Institute of Chemistry, Campus Araraquara, Paulista State University “Júlio de Mesquita Filho”, São Paulo, 14800-060, Brazil.

2Faculty of Food Science and Engineering. Technical University of Ambato. Ecuador.

3Drug Development and Research Center. Havana. Cuba.

*Address for Corresponding Author:

Jorge E. Rodríguez-Chanfrau

Department of Physical Chemistry,

Institute of Chemistry, Campus Araraquara, Paulista State University “Júlio de Mesquita Filho”, São Paulo, 14800-060, Brazil. 

Abstract

Objective: Aloe vera (Liliaceae family) is a widely used plant for its medicinal properties. The objective of this work was to obtain hydroalcoholic extract using fresh plant material and its subsequent industrial scale. Material and methods: An obtaining methodology was designed for laboratory scale, being studied for different variants. The best variant was elaborated to bank, pilot and industrial scale. Stability during 24 months was studied. Results: The results were compared with obtained extracts by means of the traditional procedure. A technological process for the obtaining of hydroalcoholic extract of Aloe using fresh plant material was developed. The technological process was introduced satisfactorily at industrial level. Conclusion: The process is homogeneous and reproducible to the studied scale up.

Key word: Aloe vera, hydroalcoholic extraction, stability, scale up

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