Review Article

2020  |  Vol: 5(3)  |  Issue: 3 (May- June) | https://doi.org/10.31024/apj.2020.5.3.1
Enhancement of dissolution rate through design and techniques of liquisolid tablets formulation

Deeksha Tiwari*, Anjudip Yadav, Vandana Sharma

Department of Pharmaceutics, Arya College of    Pharmacy, Jaipur, Rajasthan-302028 India

*Corresponding Author:

Deeksha Tiwari

Department of Pharmaceutics, Arya College of    Pharmacy, Jaipur, Rajasthan-302028 India

 

Abstract

The solubility and dissolution properties of every drug are vital determinants of its oral bioavailability. A large portion of the recently evolved drugs are lipophilic and poorly water-soluble. Upgrading the dissolution and bioavailability of these medications is a main challenge for the pharmaceutical industry. During the development of another medication, it is imperative to guarantee its fundamental bioavailability. Here comes the requirement for a Liquisolid procedure which is a novel and promising way to deal with beat the outcomes. The strategy depends on the dissolving the insoluble medication in the nonvolatile solvent and admixture of drug solution with a reasonable carrier and coating materials to change over into acceptably flowing and compressible powders. The Liquisolid technique can also be used for the enhancement and retardation of drug release. The target of this article is to introduce a review of the Liquisolid strategy, the formulation, and designing of the liquisolid system and review the progress of its applications in pharmaceutics. Low cost, easy processing and great potentials in industrial production are the main advantages of this approach.

Keywords: Liquisolid system, liquid load factor, photostability, sustained release

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