Suresh Janadri1*, Kalpana Pathak1, Neha Chakraborty1, Yogesh H.S.2
1Department of Pharmacology, Acharya & BM Reddy College of Pharmacy, Bengaluru 560 107, Karnataka, India
2Department of Pharmacology, Al-Ameen College of Pharmacy, Bengaluru 560 027, Karnataka, India
*Address for Corresponding Author:
Dr. Suresh Janadri, Ph. D.
Department of Pharmacology
Acharya & BM Reddy College of Pharmacy, Achith Nagar, Bengaluru - 560 107 Karnataka, India
Objective: Detox water is now days essential to detoxify the body and boosting immune system. The present study was carried out to evaluate the anti-inflammatory effect and immunomodulation activity of detox water in experimental animals. Material and methods: The animals were randomized into four groups consist of six animals per group. The control group- saline, standard group-diclofenac (10 mg/kg, p.o.), treatment group received detox water single dose and twice a dose respectively in carrageenan induced inflammation and carbon clearance test in rats. Results and conclusion: Study indicates detox water twice a dose shows significant (p>0.01) anti-inflammatory activity by reducing paw edema and significant (p>0.01) phagocytic index (Macrophage activation) than control and single dose of detox water group.
Keyword: Anti-inflammatory, immunomodulation, edema, detox water