Short Communication

2020  |  Vol: 5(5)  |  Issue: 5 (September- October) | https://doi.org/10.31024/apj.2020.5.5.4

Anti-inflammatory and immunomodulation activity of detox water in experimental animals

Suresh Janadri^1*, Kalpana Pathak¹, Neha Chakraborty¹, Yogesh H.S.²

¹Department of Pharmacology, Acharya & BM Reddy College of Pharmacy, Bengaluru 560 107, Karnataka, India

²Department of Pharmacology, Al-Ameen College of Pharmacy, Bengaluru 560 027, Karnataka, India

*Address for Corresponding Author:

Dr. Suresh Janadri, Ph. D.

Department of Pharmacology

Acharya & BM Reddy College of Pharmacy, Achith Nagar, Bengaluru - 560 107 Karnataka, India

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Abstract

Objective: Detox water is now days essential to detoxify the body and boosting immune system. The present study was carried out to evaluate the anti-inflammatory effect and immunomodulation activity of detox water in experimental animals. Material and methods: The animals were randomized into four groups consist of six animals per group. The control group- saline, standard group-diclofenac (10 mg/kg, p.o.), treatment group received detox water single dose and twice a dose respectively in carrageenan induced inflammation and carbon clearance test in rats. Results and conclusion: Study indicates detox water twice a dose shows significant (p>0.01) anti-inflammatory activity by reducing paw edema and significant (p>0.01) phagocytic index (Macrophage activation) than control and single dose of detox water group.

Keyword: Anti-inflammatory, immunomodulation, edema, detox water