Research Articles

2019  |  Vol: 4(4)  |  Issue: 4 (July- August) | https://doi.org/10.31024/apj.2019.4.4.1
Investigations on Drosera regia and Schleichera oleosa leaves for anthelmintic activity

Rama Shankar Dubey1, Rajesh Shukla2, Vikas Pandey2, Ajay Kumar Shukla3*

1Department of Chemistry and Pharmacy, NRI Institute of Pharmacy, Bhopal, India

2Department of Pharmaceutical Science, Guru Ramdas Khalsa Institute of Science & Technology Pharmacy, Jabalpur, India

3Department of Pharmaceutical Science, ITM College of Pharmacy, Gida Gorakhpur, India

*Address for Corresponding Author

Ajay Kumar Shukla

Department of Pharmaceutical Science,

ITM College of Pharmacy, Gida Gorakhpur (U.P.), India

 

Abstract

Objective: The aim of this study was to investigate anthelmintic efficacy of D. regia and S. oleosa leaves. Material and methods: Firstly plant leaves material was defatted with petroleum ether and prepared hydro-alcoholic extracts. Hydroalcoholic extract taken and was evaluated separately for anthelmintic activity on adult Indian earthworm Pheretima posthuma, using Albendazole as reference standard, paralysis and death time was noted. Results and Conclusion: The results represented that the hydroalcoholic extract of D. regia was more potent than S. oleosa extract. Conclude that S. oleosa leaves could be used for development of novel anthemintic treatment.

Keywords: Plant extracts, anthelmintic, Pheretima posthuma, earthworm, Albendazole

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