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Ranjan Kumar Singh1*, Ajay Garg2, Khushboo Shrimali3, Vivek Jain4, Saurabh K. Sinha4, Joohee Pradhan4
1Department of Pharmacology, Shekhawati Institute of Pharmacy, Sikar, Rajasthan, India-332001; Orcid id-https://orcid.org/0000-0002-5487-0381
2Department of Pharmaceutical Chemistry, Shekhawati Institute of Pharmacy, Sikar, Rajasthan, India-332001
3Department of Pharmaceutical Chemistry, Mahatma Gandhi College of Pharmaceutical Sciences, Jaipur, Rajasthan, India-332001
4Department of Pharmaceutical Sciences, Mohanlal Sukhadiya University, Udaipur, Rajasthan, India-313001
*Address for Corresponding Author
Ranjan Kumar Singh
Department of Pharmacology, Shekhawati Institute of Pharmacy, Sikar, Rajasthan, India-332001
Orcid id: https://orcid.org/0000-0002-5487-0381
Abstract
The “deadly nightshade” family, commonly known as "black nightshades," it’s also used as a traditional medicine system in a country like India and China. Solanum xanthocarpum is known to contain alkaloids, steroids, glycol-alkaloids, steroid saponins, glycoproteins, that exhibit antitumor activity. This review explores the phytopharmacological properties of Solanum Xanthocarpum and summarizes its wide range of pharmacological applications to understand and integrate potential image issues as multipurpose medicines. Solanocarpidine and a phytosterol known as Carpesterol are also present. The seed oil contains Carpesterol. Diosgenin, lanosterol, sitosterol. Solasonnine, solamargine, and solasodine have been isolated from the plant. The roots and fruits are used for medicinal purposes. The herb is useful both internally as well as externally. The apoptotic effects and the amount of DNA fragmentation increased in a dose-dependent manner after the treatment with the protein. Authors believe this glycoprotein is a natural anticancer agent due to its potential to induce apoptosis in the HTC29 cell.
Keywords: Solanum xanthocarpum, Ethnobotanical, Carpesterol, anti-tumour
