Research Articles

2017  |  Vol: 2(6)  |  Issue: 6 (November-December)
Consummated quantitative analysis of various generic brands of Pantoprazole and Domperidone in Srinagar division

Dr. Mohammed Shafi Chishti1, J. Vijaya Ratna4, Rayees Ahmad Dar2, Sameer Chishti3, Md. Rayees5, Shaila Farooqui6*

1Ex. DMO Mominabad Anantnag-192101.

2Assistant Professor (Statistics), Government Degree College Baramulla. 

3Medical Officer Sub-District Hospital Beerwah-193411. 

4Professor (Pharmaceutical Technology), AU college of Pharmaceutical Science-Visakhapatnam-530003. 

5HOD(Pharmaceutical Analysis) Trinity college of Pharmaceutical Sciences, Hyderabad-505172. 

6Al-Faizan Health Centre, Drug Testing Laboratory, Srinagar-190001

*Corresponding Author

Dr. Shaila Farooqui

Al-Faizan Health Centre, Drug Testing Laboratory, Srinagar-190001 (Jammu & Kashmir)

Cell number: 9797912372                                                 

Abstract

Objective: In last few years, Pantoprazole Sodium Sesquihydrate and Domperidone has become part of day to day life. Mostly doctors of all specializations usually prescribe them more often with their prescriptions.  The aim of the present study was to analyze the quality of various marketed brands of Pantoprazole Sodium Sesquihydrate and Domperidone formulations manufactured by different national companies. Materials and methods: During this study various physico-chemical properties (weight variation, hardness, friability, disintegration) along with dissolution and assay were studied, using standard techniques to evaluate their quality. In this study six different brands were randomly sampled from different Pharmacy shops in Kashmir region. Results and conclusion: After this metaphorical quantitative study it was concluded that quantitative variations exist among different brands, however, despite variations most of the drug products were within official limits and one among them failed in various parameters.

Keywords: Pantoprazole, Domperidone, Sodium Sesquihydrate, UV-Spectrophotometer

Manuscript Management System
Submit Article Subscribe Most Popular Articles Join as Reviewer Email Alerts Open Access