Short Communication

2019  |  Vol: 4(5)  |  Issue: 5 (September- October) | https://doi.org/10.31024/apj.2019.4.5.3
Comparative investigation on anthelmintic activities of Azadirachta indica and Areca catechu leaves

Pradeep Vikram1, Santosh Mishra2, Ravikant Vishwakarma2, Ajay Kumar Shukla2*

1Department of Pharmaceutical Science, Guru Ramdas Khalsa Institute of Science & Technology Pharmacy, Jabalpur, India

2Department of Pharmaceutical Science, ITM College of Pharmacy, GIDA Gorakhpur, India

*Address for Corresponding Author

Ajay Kumar Shukla

Department of Pharmaceutical Science,

ITM College of Pharmacy, GIDA Gorakhpur, India

 

Abstract

Objective: The aim of present study was to investigate comparative anthelmintic efficacy of Azadirachta indica and Areca catechu leaves. Material and methods: In present work plant leaves material was defatted with petroleum ether and prepared hydro-alcoholic extracts. Hydroalcoholic extract taken and was evaluated separately for anthelmintic activity on adult Indian earthworm Pheretima posthuma, using albendazole as reference standard, paralysis and death time was noted. Results and conclusion: The results represented that the hydroalcoholic extract of Azadirachta indica was more potent than Areca catechu extract. In conclusion Azadirachta indica leaves could be used for development of novel anthemintic treatment.

Keywords: Azadirachta indica, Areca catechu, anthelmintic, Pheretima posthuma, earthworm, albendazole

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