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Banothu Bhadru*
CMR College of Pharmacy Kandlakoya, Medchal, Hyderabad, Telangana, India-501401
*Address for Corresponding Author
Dr. Banothu Bhadru
Associate Professor
Department of Pharmaceutical Analysis
CMR College of Pharmacy, Kandlakoya, Medchal, Hyderabad, Telangana, India-501401
Abstract
A simple, rapid, explicit, and extremely expensive fluid chromatographic technique, Nateglinide mass and claimed drug structure have been established. Methanol: Phosphate support (55:45) v/v as cell area at a float cost of 1.0 ml min1; the temperature of the reliable section was ambient. This section was divided using a balance of ODS C18 (four. 6250 mm, five meters). The run time under these chromatographic conditions was less than an hour. Finally, 2.52 were chosen as the maintenance interval for Nateglinide. In the symmetry plot over the visual range of 6–14ng, there were two cutoff values for identification and measurement: 1.2 and 3.6 ng per milliliter, respectively. While the percent mending was not quite resolved in the region of 98-102 percent, the recommended percent test of promoted extra compounds came out to be 99.86 percent. The relative stranded deviation of the accuracy study was found to be 2%. The novel method is excellent, simple, quick, precise, and suitable for evaluating Nateglinide in large quantities while maintaining the drug's quantity strategy.
Keywords: Nateglinide, RP-HPLC, accuracy, precision, marketed formulation