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Plant-mediated synthesis of Zinc Oxide nanoparticles from Anethum graveolens leaf extracts its characterization and evaluation for their anti-microbial, antioxidant and in-vitro anti-diabetic activity Advance Pharmaceutical Journal

Research Articles

2024  |  Vol: 9(5)  |  Issue: 5(September-October) | https://doi.org/10.31024/apj.2024.9.5.1
Plant-mediated synthesis of Zinc Oxide nanoparticles from Anethum graveolens leaf extracts its characterization and evaluation for their anti-microbial, antioxidant and in-vitro anti-diabetic activity

S. Syed Illiyas, P. Rajesh*, G. T. Parethe, L. Robertson, S. Kavica

PG & Research Department of Chemistry, Government Arts College (Autonomous), Coimbatore-641018, India

*Address for Corresponding Author

P. Rajesh,

Department of Chemistry,

Government Arts College (Autonomous), Coimbatore-641018, India.


Abstract

Zinc Oxide nanoparticles (ZnO-NPs) have a wide range of uses, and the green manner of nanoparticle synthesis is currently preferred over other methods due to environmental benefits. The produced ZnO nanoparticles were examined using UV-visible spectroscopy, Fourier transform (FTIR), X-ray diffraction (XRD), scanning electron microscopy (SEM), and energy dispersive analysis. Images from scanning electron microscopy showed a ball-shaped structure with tiny ZnO-NPs aggregation, with particle sizes ranging from 22 nm. The crystalline nature of ZnO-NPs has been shown by X-ray diffraction. With a zone of inhibition of about 16 µg/ml against Staphylococcus aureus and 7 µg/ml against Aspergillus flavus, the produced ZnO-NPs demonstrated strong antimicrobial action. Free radical scavenging experiments were used to measure the antioxidant activity. Additionally, the study demonstrated the good anti-diabetic efficacy of the synthesized ZnO-NPs.

Keywords: Anethum graveolens, Zinc oxide nanoparticles, surface functionalization, anti-microbial, anti-oxidant, anti-diabetic

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