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In vitro antioxidant activities and quantitative chemical composition of alcohol-based extracts of Adansonia digitata fruit pulp: A comparative study Advance Pharmaceutical Journal

Research Articles

2022  |  Vol: 7(1)  |  Issue: 1(January-February) | https://doi.org/10.31024/apj.2022.7.1.1
In vitro antioxidant activities and quantitative chemical composition of alcohol-based extracts of Adansonia digitata fruit pulp: A comparative study

Daniel Ayandiran Aina, Kehinde Oluwakemi Fagbemi

Department of Microbiology, School of Science Technology, PMB 4005, Babcock University, Ilisan Remo, Ogun State, Nigeria

*Address for Corresponding Author:

Kehinde Oluwakemi Fagbemi

Department of Microbiology, School of Science Technology, PMB 4005, Babcock University, Ilisan Remo, Ogun State, Nigeria

 

Abstract

Objective: This study aimed at comparing the antioxidant potential, quantitative phytoconstituent and functional group of 70% methanol (70/30 methanol-water) and 70% ethanol solvent used for extraction of phytochemicals from Adansonia digitata (A. digitata) fruit pulp. Material and methods: The antioxidant analysis was performed with three different methods namely, DPPH, FRAP and TAC, gas chromatography-mass spectrometry (GCMS) analysis was carried out to identify the different types of compounds present in both extraction products, and functional group determination was done with the aid of Fourier Transform Infrared Spectrophotometer (FTIR). Results and conclusion: The methanol extract shows excellent antioxidant potential more than the ethanol extract in all the three methods applied, the quantitative analysis results exhibited the presence of 23 and 46 compounds for the ethanol and methanol extract respectively. Furthermore, the FTIR spectrum indicated that both extracts contain compounds with different functional groups. However, the methanol extract shows better absorption intensity than the ethanol extract. The pharmacological activities of the recognized compounds were identified, while the activities of some are unknown. Methanol is found as the most suitable solvent for extracting high numbers of different phytochemical compounds and antioxidants from the fruit of A. digitata use in pharmacognosy.

Keywords: Antioxidant, Phytoconstituent, Adansonia digitata, gas chromatography-mass spectrometry

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