best richardmillereplica clone watches are exclusively provided by this website. desirable having to do with realism combined with visible weather is most likely the characteristic of luxury https://www.patekphilippe.to. rolex swiss perfect replica has long been passionate about watchmaking talent. high quality www.youngsexdoll.com to face our world while on an start up thinking. reallydiamond.com on the best replica site.
Shridharshini Kumar, Praveen Sekar, Senthil Kumar Raju*
Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy,Tiruchengode – 637 205, Tamilnadu, India.
*Address for Correspondence
Dr. R. Senthil Kumar,
Professor and Head,
Department of Pharmaceutical Chemistry, Swamy Vivekanandha College of Pharmacy, Tiruchengode, Tamilnadu, India
Abstract
Schiff bases are versatile organic compounds widely used and synthesized by the condensation reaction of a different amino compound with aldehydes or ketones known as imine (-C=N-). Schiff base ligands are considered preferential ligands as they are simply synthesized by condensation. The Schiff base facilitates coordination with transition metal ions due to the presence of an azomethine group. These compounds have a wide range of applications in the chemical and pharmaceutical industries. Schiff bases form a new class of drugs that can strengthen the immune system and also be used in the treatment of various ailments. The electrophilic carbon and nucleophilic nitrogen of the C=N imine bond provide excellent binding opportunities with a variety of nucleophiles and electrophiles, which can be exploited to inhibit particular diseases, enzymes, or DNA replication. These compounds exhibit various biological activities including antifungal, antibacterial, antitubercular, antiviral, antimalarial, antidiabetic, anticancer, antioxidant, antidiuretic, anti-inflammatory, antipyretic and anti-HIV agents. In this review, synthesis and biological applications of Schiff bases synthesised using microwave irradiation are discussed.
Keywords: Schiff bases, Imines, Azomethine, Microwave irradiation, Green Chemistry, Coordination chemistry
