Jorge Enrique Rodríguez-Chanfrau*1, Orestes Darío López–Hernández2, Caridad García-Peña3, María Lidia González-Sanabia3, Antonio Nogueira–Mendoza3
1Department of Physical Chemistry, Institute of Chemistry, Campus Araraquara, Paulista State University “Júlio de Mesquita Filho”, São Paulo, 14800-060, Brazil.
2Faculty of Food Science and Engineering. Technical University of Ambato. Ecuador.
3Drug Development and Research Center. Havana. Cuba.
*Address for Corresponding Author:
Jorge E. Rodríguez-Chanfrau
Department of Physical Chemistry,
Institute of Chemistry, Campus Araraquara, Paulista State University “Júlio de Mesquita Filho”, São Paulo, 14800-060, Brazil.
Objective: Aloe vera (Liliaceae family) is a widely used plant for its medicinal properties. The objective of this work was to obtain hydroalcoholic extract using fresh plant material and its subsequent industrial scale. Material and methods: An obtaining methodology was designed for laboratory scale, being studied for different variants. The best variant was elaborated to bank, pilot and industrial scale. Stability during 24 months was studied. Results: The results were compared with obtained extracts by means of the traditional procedure. A technological process for the obtaining of hydroalcoholic extract of Aloe using fresh plant material was developed. The technological process was introduced satisfactorily at industrial level. Conclusion: The process is homogeneous and reproducible to the studied scale up.
Key word: Aloe vera, hydroalcoholic extraction, stability, scale up