Review Articles

2018  |  Vol: 3(2)  |  Issue: 2(March-April) | https://doi.org/10.31024/apj.2018.3.2.1
Applications of natural polymers in mucoadhesive drug delivery: An overview

Ashish Garg1, Sweta Garg1, Manish Kumar2, Suresh Kumar2, Ajay Kumar Shukla2*, Satya Prakash Chand Kaushik3

1Department of P.G. Studies and Research in Chemistry and Pharmacy, Rani Durgavati University, Jabalpur, India.

2Department of Pharmaceutical Science, Mohan Lal Sukhadiya University, Rajasthan, India

3Dept. of Pharmaceutics, Jaipur College of Pharmacy, Jaipur, Rajasthan, India.

*Address for Corresponding Author:

Ajay Kumar Shukla

Department of Pharmaceutical Sciences,

Mohanlal Sukhadia University Udaipur 313001 Rajasthan India

Abstract

Aim of this review is to compile the current literature with special focus on role of natural polymers on mucoadhesive drug delivery system. Mucodhesion refers to bond formed between two biological surfaces or a bond connecting a biological and a synthetic polymer surface. Under this drug delivery, buccal mucosa is the preferred site for both systemic and local drug action because the mucosa has a rich blood supply and it relatively permeable. Different bioadhesive dosages form available in market such as Chewing gum, tablets, Patches, Hydrogel, Thiolated tablets. In this review article the Application of natural mucoadhesive polymers advantages, disadvantages and future prospects in Buccal drug delivery has been discussed.

Keywords: Anatomy of oral mucosa, buccal, mucoadhesive polymer, permeation, dissolution.

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